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Segmenting heterogeneous target groups into more homogeneous subgroups may improve the chances of successfully identifying policy strategies to influence their behavior.
Suicide is a heterogeneous phenomenon, and thus defining more homogeneous subgroups may help in understanding its underlying biology and ultimately in its prevention.
For example, by pooling data and/or results from multiple studies on a given disease/trait, one may attain a sample size large enough to permit the division of the data into multiple relatively more homogeneous subgroups.
Thus, even though the number of cases is lower in each of the subgroups, there is more power to detect statistically significant SNPs associated with the more homogeneous subgroups of individuals with ASDs than with the combined group of cases.
Future studies should be focused on more homogeneous subgroups of patients with sepsis.
Stratifying patients into more homogeneous subgroups may facilitate better understanding of FM.
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The comorbidity between migraine and epilepsy may allow to select a clinically more homogeneous subgroup of patients in order to carry out genetic studies more targeted than those conducted in patients with common forms of migraine.
Since the withdrawal from the trial by such a large area, and its related SU, might have had strong statistical implications, we analysed both the ITT and PP cohorts, and the more homogeneous subgroup of Rome metropolitan area.
Subgroup analysis for EVVTI showed a better TPEV for the more homogeneous patient subgroups OTX (22.22%) and NEURO (12.12%) compared with SEPSIS (26.75%) and PREM (35.60%).
We hypothesize that this discrepancy is related to the heterogeneity of BD, and examine the question of whether or not more homogeneous clinical subgroups display a more coherent pattern of morphometric abnormalities.
Through the analysis of IDH gene mutation it is possible to add molecular characteristics to refine the WHO classification in order to define more homogeneous gliomas subgroups.
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