We find there are significantly more age-homogeneous complexes whose constituents are all of the same age class than random expectation based on 1000 experiments established by randomizing the corresponding relationships between proteins in the yeast genome and their ages.
Second, the observation that the distribution of RC complexes was more homogeneous in cells coexpressing two fluorescent complexes than in fused hybrid mitochondria 4 h after cell fusion was confirmed for nearly all combinations (Figure 5I and J, coexpression).
Synchronization of infection might provide a more homogeneous phenotype of intracellular complexes.
These data show TatAd complexes to be smaller and more homogeneous than E. coli TatA complexes, with no indication of a pore large enough to translocate the larger Tat substrates in a folded state.
Electron microscopy of negatively stained samples confirmed that the cross-linked CCR4-NOT-complex was more homogeneous than the non-cross-linked complex.
Similar to protein properties, we also found that the dN/dS ratio of genes associated with annotated human complexes are significantly more homogeneous compared with those from randomly generated complexes.
Compared to conventional protein-protein interaction networks, the networks from the protein complexes show more homogeneous structures than those of the binary protein interactions, implying the formation of complexes that cause a relatively more uniform number of interaction partners.
Experimentally, we observed that RPA and Rad52 form a relatively weak and heterogeneous complex when ssDNA is absent and that the complexes formed become more homogeneous when RPA has ssDNA bound.
Nevertheless, the two types of complexes exhibit major differences in other respects; TatA complexes are found in a large size range (9 13 nm diameter), whereas TatE complexes are much smaller and more homogeneous (6 8 nm diameter).
Micro-Raman images display a more homogeneous spatial distribution of the K[Eu dbm 4] complex throughout the film, when compared to K[Eu(hfac 4] film.
