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This chemical highlights the critical need to consider ADME, especially metabolism, in establishing a more holistic interpretation of high-throughput in vitro results based on AOPs.
Consumer perspectives also complement the perspectives of clinicians and researchers by providing a more holistic interpretation of health [ 22] and they are able to use a "personal lens" [ 24].
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After completion of the PAR, data were reanalysed to develop a deeper, more holistic understanding and interpretation of the findings.
Measuring CIMT, as a surrogate marker of cardiovascular disease, is widely used and validated method in both patients with or without T2DM to detect subclinical atherosclerosis, however to predict the relative risk for the development of future cardiovascular diseases is much more difficult and presumes holistic interpretation of the complex interactions between both genetic and clinical factors.
MICA provides an opportunity to pilot the application of a more holistic analytical approach to improve the interpretation of biomarker data to advance both mechanistic based toxicology and risk assessments of chemical (single, multiple, and complex mixtures) exposures.
Measurements at each of these levels permit a more holistic understanding of the drug's performance and provide context both for interpretation of biomarker readout and for broader use in dose selection.
Interpretation to the clinical staff involved assisting clinicians to refine the planning of care to reflect a more holistic approach to service delivery, which incorporated a cultural dimension.
Life is more holistic".
More holistic, if you like.
"There can be a more holistic approach".
Patients need a more holistic approach.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com