Consistent with our observations, global levels of gene expression heterogeneity between cells grown in 2i and in serum were comparable, while GO categories for development and differentiation were more heterogeneous in serum than in 2i, and cell-cycle genes were more heterogeneous in 2i than in serum.
We did not quantify the architectural differentiation of biofilms across flumes, but it becomes obvious from the spatial variation of both chlorophyll-a and bacterial abundance among microhabitats, that biofilm differentiation was highest in the more heterogeneous flumes.
The more heterogeneous flow landscapes triggered larger bacterial biodiversity and structural differentiation of biofilms, ultimately resulting in a broader range of DOC compounds removed more rapidly by the biofilms.
With this understanding, one can design experiments to study more detailed signal-control principles of a particular signaling network governing heterogeneous differentiation.
In the model, heterogeneous differentiation is defined as the process in which more than one functional (non-naïve) phenotypes can be observed upon uniform treatment of a population of simulated naïve cells (see Methods).
The luminal cell compartment in the mammary epithelium is more heterogeneous than initially perceived since progenitors of varying levels of luminal cell differentiation and proliferative capacities can be identified.
The results presented here demonstrate that the luminal cell compartment in both the human and mouse mammary glands is much more heterogeneous than initially perceived since progenitors of varying levels of luminal cell differentiation can be identified and prospectively isolated.
In addition, the participants' responses for syntagmatic association were far more heterogeneous than for paradigmatic association, which seemed to resonate a concern that *Read (1998) voiced about his differentiation between the two types of association relationships in his revised WAT.
Further investigations, maybe on larger and more heterogeneous population, should address to the relationship between MDR-1 expression, renal carcinogenesis, neoplastic progression and degree of differentiation in RCC.
