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Technological advances have greatly enhanced the specialty of radiation oncology by allowing more healthy tissue to be spared for the same or better tumour coverage.
If you hit a patient with protons going at the right velocity toward the tumor, you should spare more healthy tissue.
The hope was that this would preserve more healthy tissue.
A general conclusion from these reports is that advanced treatment techniques can improve target homogeneity and reduce high doses to the heart and lung, but more healthy tissue received low doses.
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Needle biopsies from their livers, taken while the animals were anaesthetized and examined under a microscope, showed that the treatment resulted in more healthy-looking tissue.
More specifically, the healthy tissue with dendrimers favours the black areas (smooth regions), while the atheromatous one favours white areas (rough regions).
Tracers are designed to accumulate in tumours more than in healthy tissue: the most used are Tc-99 m sestamibi and Tc-99 m tetrofosmin.
Fibrotic tissue is significantly more heterogeneous than healthy tissue, due to the formation of fibrotic foci that unevenly deposit ECM within the tissue.
Since cancerous lesions are metabolically more active than healthy tissue and blood supply to the lesion is increased, cancerous lesions are warmer, and under certain conditions the difference in the IR radiation emitted by the lesion and healthy tissue can be readily detected by thermographic imaging.
Our data demonstrated that CaP tissue expressed significantly more DKK-1 than healthy tissue, p<0.001 (Fig. 3B).
More generally, clearance from healthy tissue could be added.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com