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In contrast, the second modification, which combines ChIP with specialized CpG microarrays, is ideal for a more global analysis of target genes.
To establish a more global analysis of muscle phenotype we subjected the muscle samples to Affymetrix gene array analysis followed by our comparative array analysis strategy [30], [31].
This was twice as high as that after one hour without stimulation (PI = 0.05), but may well have gone undetected in their more global analysis.
However, they compared GEP with chromosome 3 FISH rather than a more global analysis evaluating chromosome 8 imbalances such as that provided by MLPA or array-CGH.
Future studies will have to try a more global analysis of this network as opposed to focusing on a limited number of readouts.
However, the strong coregulation in the abundance of lipid species identified in this study necessitated a more global analysis of potential lipid function.
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The consideration of real semi-rigid behaviour can lead to a more accurate global analysis and, consequently, more optimized structures.
The consideration of their real semi-rigid behavior can lead to a more accurate global analysis and, consequently, more optimized structures.
Thus, the main purpose of the present study was: a) to evaluate the effect that the lack of AQP4 has on DGC and ECM expression and localization; and b) to conduct a more global protein analysis to assess altered protein patterns in skeletal muscle of AQP4-null mice.
The next logical step would be to consider a more global sensitivity analysis by investigating combinations of parameters, which was beyond the scope of this study.
These findings emphasize that, as technology develops, patients may benefit from more global genomic analysis of tumor samples prior to treating with targeted compounds.
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more concrete analysis
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