Sentence examples for more genetic variants from inspiring English sources
The researchers have now used the same strategy to identify more genetic variants associated with brain structure and IQ.
The aim of the study is to explore the reliability of the high resolution melting (HRM) analysis for the identification of BRCA1/BRCA2 mutation carriers among the family members of index patient (IP) and for distinguishing the presence of two or more genetic variants within the same amplicon.
We show that Neandertals shared more genetic variants with present-day humans in Eurasia than with present-day humans in sub-Saharan Africa, suggesting that gene flow from Neandertals into the ancestors of non-Africans occurred before the divergence of Eurasian groups from each other.
This suggests that the risk estimates provided by the GCI may vary considerably in the future, as more genetic variants are found and used for risk estimation (e.g. see [24]).
The presence of allelic or locus heterogeneity creates heterogeneous disease models because two or more genetic variants (i.e., at two or more alleles or genes, respectively) are independently associated with the same trait in the affected population.
Theoretically, reconstruction of the molecular interaction networks linked to gwas-genes by systems biology approaches may help to elucidate the functional consequences related to each susceptibility allele and the combined effects of more genetic variants.
One or more genetic variant(s) unique to this population may therefore increase PMD.
The more harmful genetic variants are discovered, the more compelling the logic may seem of fixing the bugs in the genomic programming directly instead of treating the symptoms in each generation, a procedure called germ-line gene therapy.
It is beyond doubt that many more genetic susceptibility variants will be discovered in the next few years.
More genetic risk variants and other risk factors should be well evaluated and incorporated into the risk-predicting models to improve the ability of personalized risk assessment.
However, risk profile based on a combination of genetic and other risk factors leads to an appreciable increased risk of disease and there is potential for increased predictive power as more genetic risk variants are detected [ 32].
