Sentence examples for more genetic modifiers from inspiring English sources

There are likely many more genetic modifiers of human longevity that remain to be discovered.

However, these variants have been mainly related to lipoprotein metabolism [20] [22], FOXO proteins [23], [24], and insulin/IGF-1 signaling [25] It is likely that many more genetic modifiers of human aging have yet to be discovered [25].

This may carry one or more genetic modifiers for the manifestation of the retinal pathology associated with mutations in Crb1.

This analysis result suggests that researchers expecting to discover more genetic modifiers should focus their efforts also on genes involved in cell cycle and splicing, biological processes that are also often enriched in modifiers.

But in other segregating populations the situation was more complex, suggesting that genetic modifiers can overcome the action of the Wx allele [ 25].

However, relatively few of these genetic modifiers are common to more than one disease model, despite the shared feature of protein misfolding/aggregation [13, 14].

This may resemble a mixture of one or more disease-related mutations and environmental or genetic modifiers (Crotti, 2011).

Further research is needed to clarify if certain genotypes more reliably predict phenotypic behavior, or if environmental and/or genetic modifiers can be incorporated into risk algorithms.

With the use of artificial insemination and Caesarean sections that allow some brachycephalic breeds to reproduce, selection for more extreme versions of this phenotype has occurred and it is likely that genetic modifiers exist for this trait [9], [10].

Moreover, unconventional mutation mechanisms relating to genetic modifiers, and multigenic and multiallelic inheritance will need to be more systematically studied.

Genetic modifiers and/or environmental risk factors may influence the epilepsy subtype or severity; this will require more systematic studies in the future.