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Thus, the observed genome architectures are, mostly, products of neutral processes or epiphenomena of more general selective processes, such as selection for genome streamlining in successful lineages with large populations.
Is the correlation between expression divergence and protein divergence linked to specific gene characteristics or does it reflect more general selective constraints?
This suggests that the correlation between expression divergence and protein divergence is not linked to a specific gene characteristic, but instead reflects more general selective constraints, supporting recent studies in mammals (Warnefors and Kaessmann 2013).
Our results therefore suggest that the correlation between expression divergence and protein divergence is not directly linked to between-gene variation in one or more specific gene characteristics but instead is the result of more general selective constraints on gene function.
They also excluded protein length and the number of protein protein interactions as responsible factors and speculated that the correlation was instead due to more general selective constraints that affect gene expression and protein sequences in similar ways (Lemos et al. 2005).
Similar(55)
Although Orlistat appears to be selective for cyclin D1-overexpressing cells, our data indicate that MLN4924 has a more general selectivity to tumor cells.
SLRs have been specifically implicated in innate immunity, but may have a more general role in selective autophagy (Gibbings et al., 2012 ; Tumbarello et al., 2012 ).
For more general case of frequency-selective channels, the interested reader is referred to [24].
Indeed, these changes in patterns of functional connectivity could reflect a more general mechanism for category-selective interactions within the brain (see Norman-Haignere et al. 2012).
We conclude that, in marked contrast to the more general response to starvation, anoxia induces tissue-selective upregulation of autophagy in the intestine.
Nevertheless, we again observed a number of selective effects independent of the more general cytotoxic actions.
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