Sentence examples for more gene polymorphisms from inspiring English sources

Such as one or more gene polymorphisms resulting in a defective but functioning eNOS enzyme.

What is more, gene polymorphisms 33 and biological markers 34 35 are also suggested to be predictors of prognosis in patients with RCC.

Current thinking is that this variation, in large part driven by the 16 or more 5-HTT gene polymorphisms discovered to date, is the source of large individual differences in personality, behavior, and brain disorder susceptibility.

The relatively low frequencies of the CYP2C9 *3 allele and CYP2C9 genotype-derived PMs indicate that, in this population, COAs dosage adjustments and responses may depend more on VKORC1 gene polymorphisms.

Ersoz et al. (2010) studied patterns of polymorphism in candidate genes for the host pathogen interaction between Pinus taeda and Fusarium circinatum and Cronartium quercuum sp. Fusiforme and found indications for both active coevolution (arms-race model) and presence of more stable resistance gene polymorphisms (trench warfare model).

Because the majority of the published GWAS concentrate on single-locus strategies to identify novel breast cancer susceptibility loci, a candidate gene approach restricted to specific pathway related gene polymorphisms to more effectively mine GWAS data is presented considering moderately associated SNPs.

Studies on functional gene polymorphisms will be more likely to yield positive results than random polymorphisms simply because of the greater prior probability of being associated with disease.

In the current study, we have attempted to move beyond single gene polymorphisms to a more comprehensive pathway evaluation to identify genomic variants and patterns that may help predict clinical response and overall survival to platinum-based chemotherapy, thus ultimately leading to a more tailored approach to chemotherapy.

Further studies could define more clearly the prognostic value of MDR1 gene polymorphisms in determining therapeutic response to ART.

More recently, increasing studies on Aurora-A gene polymorphisms and risk of malignant tumors have been reported.

More recently, it has been described that HFE gene polymorphisms (mutations) are frequently detected in patients with MDS [ 13, 14].