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To date, the problem for essential hypertension has been more fundamental, with a difficulty in confidently identifying any susceptibility loci.
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The Web already has 300m pages, and the number is growing by 1m a day.A more fundamental difficulty with HITS is that it tends to struggle when faced with very sharply focused queries.
There is another, more fundamental problem with economic forecasting.
"Nobody should be deluded that this addresses the more fundamental problems with the system.
There is a more fundamental problem with T-Mobile's service, though.
But there is a more fundamental problem with the idea that guns actually protect the hearth and home.
This would not, however, solve the more fundamental problem with the quality of what is taken for medical knowledge.
Darwin may be misunderstood here, but in many ways that is but one symptom of a more fundamental problem with education in Egypt and around the region.
But even a national network may not overcome more fundamental problems with the system, said Dr. Sidney Wolfe, director of Public Citizen Health Research Group in Washington.
Some Boeing people suspect an Airbus-inspired conspiracy).But the company made a more fundamental miscalculation with this latest version of the world's best-selling aircaft.
It remains to be seen whether the problem reflected the usual growing pains of a young company or a more fundamental problem with its practices.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com