Sentence examples for more fundamental pathological from inspiring English sources

Finally, the observation that NII accumulation was reduced by PDE10A inhibition suggests that the formation of these aggregates may be driven by more fundamental pathological processes.

Understanding that these clinical and pathological factors are but crude surrogates of more fundamental biological predictors of melanoma behavior and survival outcomes would provide the reader with a more unifying conceptual way of thinking about this subject.

The recent demonstration that a much larger proportion of the inclusions in NIFID are FUS-ir, that all the cells with IF-ir inclusions also contain pathological FUS, and that there are widespread FUS-ir glial inclusions, suggests that the abnormal accumulation of FUS may be more fundamental in the disease process and that IF pathology probably develops as a secondary process [ 10].

Since much of their migration is likely to occur through tissue with physiological rather than pathological gradient(s) before reaching the site in need of regeneration, perhaps a more fundamental question is whether they durotax when presented with a physiological stiffness gradient <1 kPa/mm in the absence of other stimuli, e.g. soluble growth factor gradients which could induce chemotaxis.

Other applications are more fundamental.

Players also offered Ryan more fundamental gratitude.

A far more fundamental objection was stylistic.

The more fundamental problem is talent.

But there are more fundamental challenges.

The real issue, however, is more fundamental.

Einstein's approach was far more fundamental.