Viral neutralizing (VN) assays were also performed to provide a more functional measure of vaccine-induced immunity.
Because of the inherent limitations of these assays, vaccine developers increasingly rely on the MN as a more functional measure of immunogenicity [24], [25].
To provide a more functional measure of vaccine-induced immunity, 200 TCID50 per well of virus were incubated with two-fold-diluted mice sera at a starting dilution of 1 : 20.
Following ischaemia and reperfusion, CLP hearts showed more rapid recovery of functional measures, despite significantly reduced baseline function, and infarct size was significantly reduced in septic hearts (Figure 3).
Therefore more studies looking at functional measures are needed in order to reach a broad conclusion about the effects of FES on upper arm motor function late after stroke.
Less sleep, the researchers said, "is associated with more negative cognitive, behavioral and functional measures among adolescents".
In our GDH population, the rehabilitation outcome is more directly related to the functional measures on admission, regardless of a high average burden of disease and medication count.
As such, perhaps more consistent ways to translate functional measures (measures captured in clinical trials fairly reliably) into costs may be the most effective way to conduct cost-effectiveness studies.
The study design incorporated ancillary objectives including natural history, development and validation of more sensitive diagnostic criteria and functional measures of disease severity and progression, cognition, quality of life, health economics, MRI changes, pathology and the establishment of brain and DNA banks.
Seynnes and colleagues [ 31] compared several trials and found that training with high intensity (80% of 1RM) is as save as training with low intensity (40% of 1RM), while - as expected - high-intensity training is considerably more effective concerning physiological and functional measures.
