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In responding patients (highlighted in green), FDG SULmax decreased significantly more from baseline to post-cycle 1 than in non-responding patients (P = 0.017).
Mean RER significantly reduced more from baseline to 30 min (p = 0.017) but was not significantly different at 60 min post (p = 0.360) for HIIT when compared to HIRT.
7.7 % Overall (16.6 % in CBT group vs. 0 % in AR group vs. 5.3%% in EDU group) No significant difference in HA intensity was found in any group at post-assessment Responder rates (reduction in HA frequency of 50%% or more from baseline) were significantly higher in CBT (63 %) + AR (32%%) groups, compared to the EDU/ control group (19%%).This resulted in NNTs of 2.0 for CBT + 5.2 for AR.
The challenge test was discontinued if FEV1 dropped 20% or more from baseline.
Recovery of pain is defined as improvement of 11 points or more from baseline [ 24].
Only studies that assessed outcome measures six months or more from baseline were included in this review.
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At 12 months (table 2), 43% (10/23) of the eyes improved by 10 or more letters from baseline, 35% (8/23) improved by more than 15 letters compared with baseline and 8% (2/23) of the eyes had lost 10 or more letters.
As expected improvements pre- and post-intervention were seen in both groups, however improvement was clinically more relevant from baseline to 12 months for BKP patients.
Improvements of 0.22 or more points from baseline represent the HAQ-DI MCID [ 28].
In the urinary domain, RP also led to worse summary scores (P=0.014), and more deterioration from baseline (41%, 12 %, 19, respectively).
Of those that did not have a BML at baseline (n = 227), 7% developed one or more BMLs from baseline to follow up.
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