Sentence examples for more frequently mutated from inspiring English sources

Due to the detection of the V600E BRAF mutation in this fistula melanoma, it was decided not to look for alterations in genes such as CCND1 or KIT, more frequently mutated in acral and mucosal melanomas [ 29], since concomitant mutations in BRAF and in genes such as KIT or CCND1 are extremely rare [ 29].

Statistical analysis of the whole series (230 patients) revealed that KRAS is more frequently mutated in the primary tumors of patients with lung metastases compared with patients with liver metastases (57% vs 35%, P = 0.006).

Inversely, we find that chromatin factors are more frequently mutated in tumor samples than random genes.

The mtDNA was more frequently mutated in renal carcinoma than in kidney cortex tissues.

For lung tumors, the more frequently mutated kinase is EGFR, with 61 of the 95 described AMs.

Therefore, we cannot exclude that other exons of the genes may exhibit a more frequently mutated genotype.

Thus, it was speculated that shift of C G to T A might make the pathogen more frequently mutate in virulence differentiation of C. lunata, at least partly, suggesting that C. lunata CX-3 has a strong potential to evolve into other pathogenic types of strains.

KRAS was more frequently found mutated in females than males for the ages ≤40, 40 50, and 50 60.

Mutations in RAS proto-oncogenes (comprising H-, N- and K-RAS) are among the most common in malignant tumours and although RAS isoforms are very similar, KRAS is more frequently found mutated in cancers occurring in 22% of all tumours analysed compared to 8% for NRAS and 3% for HRAS[ 7].

Among these MARBPs, p53 is frequently mutated in more than 50% human cancer patients [3].

Consequently, without normalizing for coding sequence length, frequently mutated ERGs correlated with more cancer genes than rarely mutated ERGs (p = 2.3 × 10−5 using permutation test).