Sentence examples for more frequently methylated from inspiring English sources

DAPK1 and CADM1 were significantly more frequently methylated in SCCs while methylation of APC, CDKN2B, RASSF1A, TIMP3 and TP73 was significantly more frequent in AdCAs.

We found the methylation of DLC-1 promoter more frequently methylated in the CRC samples (C1, 60% and C2, 31%) than in the adenomas (A1, 9% and A2, 4%)).

However, MGMT and CACNA1A individually were observed to be more frequently methylated in invasive cancer compared with DCIS (MGMT methylation: 8/14 invasive, 2/12 DCIS, P = 0.022; CACNA1A methylation: 6/14 invasive, 1/12 DCIS, P = 0.048).

In addition, RASSF1A was more frequently methylated in early tumor stage (data not shown), suggesting that RASSF1A methylation may be an early event in lung tumorigenesis.

Indeed, the causative factor of the observed microsatellite instability is the exclusive hypermethylation of MHL1 in these tumors, and other genes like p16 and THBS1 are also found more frequently methylated in CIMP+/MSI+compared to CIMP+/MSI-[25].

Similar to ALL cell lines, genes involved in p53 dependent apoptosis were more frequently methylated (70% of the patients) than p53 cell cycle dependent genes (15%) or p53 regulatory genes (32%).

Had we increased the number of tumour suppressor genes to be checked, which were frequently methylated in HCC tissue, it would have been more advantageous not only for determining clonality but also for assessing the malignant potential of the tumours.

By increasing the number of cases and frequently methylated genes related to tumour initiation and progression, the clonality would be shown more certainly.

The TSGs most frequently methylated in the overall series were STK11 (96.8%), MGMT2 (64.5%), RARB (63.0%), and GATA5 (63.0%).

Three genes appeared to be frequently methylated in primary MCL.

The most frequently methylated loci were RUNX3 (18/108 methylated) and ABO (22/107 methylated).