Furthermore, different gene pairs at the same molecular level are more frequently co-expressed simultaneously or with a short time delay at the protein level than at the transcript level.
Compared to other patients in Cuba, CRF19_cpx infected patients have a higher viral load at comparable times since infection, higher levels of RANTES and are more frequently co-infected with oral candidiasis.
Imbalance was shown to have deleterious effects and it was also demonstrated that interacting proteins were more frequently co-expressed than random pairs, also indicating that they either both go through duplication or both remain as solo copies.
Coexisting mutations of KRAS/ BRAF and PIK3CA have been reported in several studies [ 24, 30, 31, 36], with PIK3CA exon 20 mutations more frequently co-occurring with mutations of unknown significance or with KRAS codon 146 mutations [ 24].
Furthermore, for all meta-analyses, we found original articles on the same topic that were more frequently co-cited than the articles that were included (see examples in Additional file 1: Table S2); however, we did not attempt to investigate whether they had been excluded after screening or perhaps should have been included in the meta-analyses.
In turn, sperm-typing studies and analyses of LD indicate that NCOs occur ∼1 to 15 fold more frequently than COs (Ardlie et al., 2001; Frisse et al., 2001; Jeffreys and May, 2004; Gay et al., 2007; Odenthal-Hesse et al., 2014), with this value varying widely in analyses of individual hotspots (Jeffreys and May, 2004; Odenthal-Hesse et al., 2014).
Maternal conditions (gestational diabetes, pregnancy induced hypertension, and pre - eclampsia) were more frequently reported as co morbidities of excess GWG than were implications for the child (macrosomia, foetal abnormalities and higher risk of undetected foetal abnormalities).
Co-infection of PCV2 with TTSuV1 was more frequently observed than co-infection of PCV2 with TTSuV2 (44.8% and 31.0%, respectively).
Interestingly, enrichment of miRNA core motifs are reported in the 5' UTR compared with non-target motifs, and particularly the enrichment of reverse complementary miRNA core motifs in the 5' UTR appears more frequently in the co-expressed genes of miR-124 than that in 3' UTR [43], which raises a question as to whether the miRNAs are likely to induce expression from the 5'UTR.
However, since becoming established, R. imitator has become more abundant than its sympatric model species [ 25], thus we expect predators to come in to contact with R. imitator more frequently than the co-mimetic model species.
The difference in microhabitat usage between these species may put R. imitator in contact with increased quantities of ant-derived toxins (e.g., DHQs, HTXs, and 3,5-Is) more frequently than its co-mimetic species.
