Sentence examples for more frequently amplified from inspiring English sources

Compared to female breast cancer CCND1 and EGFR were found to be more frequently amplified in male breast cancer, while in females EMSY and CPD were more often involved and more frequent amplifications of TRAF4 and EMSY were found.

A total of 189 genes were more frequently amplified in IBCs than in nIBCs.

In contrast, no gene was more frequently amplified in nIBCs than in IBCs.

The presence of a malignancy in the airways was only moderately associated with the rate of copy number abnormalities except for MYC, which was more frequently amplified in preinvasive lesions of patients with lung cancer.

None of the studied genes was significantly more frequently amplified in men.

Act genes should be more frequently amplified and receive protein-affecting non-truncating mutations, which may increase and/or alter the protein function.

The ten most frequently amplified kinases were gained at least six times more frequently than lost, likely indicating a selection for gains of these genes.

In fact, the AKT gene is frequently amplified and the AKT protein is constitutively active in more than 60% of pancreatic carcinomas [ 37, 38].

3q26 is frequently amplified in several cancer types with a common amplified region containing 20 genes.

It is known that more than 50% of miRNA genes are localized within genomic regions that are either frequently amplified or deleted in different tumor types, resulting in miRNAs deregulation and aberrant expression [ 17, 18].

More than half of miRNAs are located at sites in the human genome that are frequently amplified, deleted, or rearranged in cancer, suggesting that miRNA abnormalities play a broad role in cancer pathogenesis (Calin et al, 2004).