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We did not find that GERD increased the risk of rCAP, although it may be associated with more frequent recurrences.
Findings associated with more frequent recurrences and metastases include lobulated/irregular contours, oval shape, mediastinal fat or great vessel invasion and pleural seeding (Fig. 1a).
GEJ carcinomas were associated with younger age at resection, more frequent intestinal-type and less frequent diffuse histology, more frequent p53 overexpression and less frequent loss of p53 expression, more frequent stage III disease, less frequent stage I disease, and more frequent recurrences.
The different results on outcome between the two studies may be attributed to a larger proportion of high-grade tumors (24% compared to 10%) and more frequent recurrences (38% compared to 27%) in the present cohort (Stockholm) than those in the previous one (Malmö; Table 1).
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Though there has been concern that the nipple-sparing procedure might lead to more frequent recurrence of cancer, a recent review found that just 2.8 percent of patients experienced a recurrence over two years.
In addition, it is necessary to consider the location of the chondrosarcoma when determining the treatment strategy because chondrosarcomas arising from the pelvis or axial skeleton are generally associated with greater biologic aggressiveness and more frequent recurrence.
Furthermore, more frequent recurrence of periodontal disease in smokers than in non-smokers during periodontal maintenance has also been reported [ 4, 5], and an association between smoking and tooth loss during this period has recently been reported [ 6].
Currently, lower ANXA2 expression in prostate cancer patients, compared to that in benign prostatic hyperplasia, correlates with an advanced clinical stage, more frequent recurrence, and regional lymph node and distant metastasis and may serve as a useful biomarker [ 73].
In our study, patients with an FGFR1-amplified NSCLC showed a significantly worse 5-year (P=0.0204) and long-term (10-year) OS (P=0.0205), more frequent recurrence (70.6% vs 51.8%) and significantly shorter long-term DFS (P=0.0466).
Lung cancer is a leading cause of cancer death worldwide 1. Small-cell lung cancer (SCLC) is an aggressive subtype, characterized by a neuroendocrine nature, which represents ∼15% of all newly diagnosed lung cancers 2. SCLC patients have a poor prognosis compared with non small-cell lunon small-cellClung due to more rapid growth and more frequent recancerse.
Different is also the recurrence pattern: <70 years old group there were <span class="lh">more frequent locoregional recurrences (27% vs 12.5%); ≥70 years old group there was a greater incidence of peritoneal (25% vs 2%) and hematogenous (18.7% vs 15%) recurrence.
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