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As an alternative, the use of magnetically controlled growing rods (MCGR) allows for more frequent non-invasive distractions to mimic normal growth.
Those are just the deaths, putting aside the amputations, paralyses, fractures, concussions, and other more frequent non-fatal incidents.
CNVs are not randomly distributed throughout the chromosome, as they tend to be over-represented in "hot-spots," regions where high rates of segmental duplication (in effect, insertions that have been driven to near-fixation) lead to more frequent non-allelic homologous recombination (e.g., [46]).
Overall, transitions resulted in more frequent non-synonymous substitutions (41.5%) than did transversions (27.7%).
Those patients with BAV disease had larger ascending aortic dimensions and may require more frequent non-invasive surveillance.
Is the fate of the copy with a faster rate of substitutions, lower expression, and more frequent non-synonymous polymorphisms sealed?
The lack of lower serum phosphorous concentration in significantly younger subgroup yet without vascular calcification can be explained by the more frequent non-adherence of younger patients to phosphorous binding drugs and diet recommendation [ 16].
More frequent non-compliance points out the need for a better integration of guideline-based care in oncogeriatry (Biganzoli et al, 2012; Parks et al, 2012) and the need for specific clinical research (Mohile et al, 2012).
More frequent non-traumatic lower limb pain among younger children (aged 9 10 years) is in accordance with the literature suggesting that "growing pains" mainly affects children aged 4 to 10 with occasional relapses in teenage years [ 8].
In the more frequent non-paraneoplastic cases, it is possible that occult tumours may have been eliminated by the immune surveillance mechanisms that generated the neurological syndrome, or are still present as has been reported even in some patients who improved spontaneously (Iizuka et al., 2008; Shindo et al., 2009).
Antibodies to the Ro/SSA and La/SSB ribonucleoprotein particles usually are found in the serum of pSS patients and are associated with a longer disease duration, more frequent non-exocrine manifestations, and more intense lymphocytic infiltration of the minor salivary glands [ 21].
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