Sentence examples for more frequent mutations from inspiring English sources

Although the authors of the study acknowledge their findings do not establish a causal link between a father's age and a child's emotional and academic vulnerability, they conclude that their findings are consistent with the hypothesis that more frequent mutations in the sperm of older men is "causally related" to their childrens' higher risk of poor outcomes.

The basal-like cell lines were ER-negative and exhibited more frequent mutations of TP53 and PTEN, consistent with findings in basal-like tumors [3], [77].

This implies that no general patterns of gene mutation and no sequential set of gene modifications are expected, although each tumour, depending on its type and tissue of origin, may present more frequent mutations in the particular genes that are active in the particular differentiated tissue.

This is in the core 507 533 region, in which numerous mutations have been observed to cause resistance to RIF, although mutations at other sites in this region are more frequent (mutations specifically at Asp 435 constitute only 9% of all RIF-R cases).

Some groups have reported more frequent mutations in K-ras and in the methylation of methylguanine transferase in MSI-L tumors, but others have questioned these findings.

Our results identified more frequent mutations in the coding region than prior studies with mutation clustering in the tRNA and ND complex genes.

For more frequent mutation variants, even odds ratios as small as 1.3 would have been detected with the same power.

In comparison to CIMP-L tumors, CIMP-H tumors were more often located in the proximal colon and showed more frequent mutation of KRAS and BRAF (P < 0.001).

Numerous mutations in each gene have been found in most populations studied, but only one mutation in each gene has been identified to date in the Icelandic population of 285,000; a rare mutation in the BRCA1 gene, and a much more frequent mutation in the BRCA2 gene.

The DNA array uses specific oligonucleotide probes for FH-causing mutations with the more frequent LDLR mutations known to affect certain country and which are regularly updated.

A recent paper by Daoud and colleagues [33] investigated the role of mutations affecting Dp140 in DMD, and concluded that mild mental retardation is significantly more frequent with mutations affecting Dp140.