Sentence examples for more frequent losses from inspiring English sources

Luminal A tumors were characterized by more frequent losses on 16q, while other GISTIC regions were less frequently altered compared to HER2+ tumors.

Thus, genes with significant increases in entropy were approximately 1.6 times more likely to undergo more frequent losses in disseminating tumours (Fisher test P = 0.08).

Of the top 133 genes exhibiting increases in entropy, 90 could be mapped to the array CGH study and of these, 68 (75%) showed more frequent losses in primary tumours that metastasized (Additional file 4).

It was therefore encouraging to observe that genes undergoing the most significant increases in entropy were also more likely to undergo more frequent losses in the tumours that metastasized.

Luminal B tumors were characterized by more frequent losses on 6q, 11q, 16q and 22q compared to HER2+ tumors, while normal-like tumors were characterized by an overall lower CNA frequency.

Also, a correlation between some clinical data and chromosomal alterations was reported, such as association between the gains of 1q and 2q and a refractory clinical response (Bergamo et al, 2000), and more frequent losses at 13q, 8p and 9q in metastatic than in primary tumours (Kujawski et al, 1999).

In previous studies, we have shown concordant loss of Fhit and Wwox expression in breast cancer, with significantly more frequent loss in cancers of basal-like phenotype.

Depleted in ER− tumors were the cytobands 4p16, 5q11 13, 5q22, 5q31, 14q22 23 which show more frequent loss in basal tumors, and 16p11 p13 which shows more frequent gain in luminal tumors [30].

However, some differences were visually apparent, such as the more frequent gain of 1q, 8q and 17q regions in IBCs, or the more frequent loss of 4p, 8p, 11q, and 16q regions in nIBCs.

For instance, HER2- luminal A and B tumors displayed more frequent loss of 16q than HER2+ tumors as a whole.

HG-SILs destined to recur showed significantly more CNIs and significantly more frequent loss of 4q and 5q than HG-SILs that did not recur.