Compared to the adenomatous type, foveolar type lesions were more frequently located in the antrum/pylorus, flat/depressed lesions, and normal/reddish in color; and showed more frequent high-grade dysplasia.
An. rufipes was also collected in all landscape classes but was more frequent in villages located in wooded and shrubby savanna.
Interestingly, we observed that those CNVs are statistically more frequent than CNVs located out of rearrangement hotspots (mean frequencies 2.47% and 1.34%, respectively; Mann-Whitney U test p < 0.01).
Increased expression was significantly associated with increased tumour thickness (Table 1), and strong expression of ID1 was found significantly more frequent in primary melanomas located on the trunk, compared with other sites (χ test, P=0.001).
These In100-like elements tend to locate more frequent in intronic regions than exonic regions.
The LOH of chromosome 13q, where Rb gene is located, is more frequent in HCC (25-48%) [ 43, 44].
The analysis revealed that genes containing mutations were ∼10% more frequent within NSBs than those located in SBs and were more prevalent when excluding genes closest (100 or 500 kb) from chromosomal termini (Fig. 3a).
Indeed, colocalization was more frequent in oval enteric neurons located peripherally in the ganglion, which suggested that c-Ret function is required not only during early foetal stages but also in the mature human ENS of the gut.
Therefore, we suggest that the approach of improving protein expression by an exchange of rare codons by more frequent codons should exclude rare codons located in highly conserved rare codon rich regions.
If this were a frequent phenomenon, allelic variation in gene expression should be more frequent in single-copy regions that are located in the vicinity of SDs than in single-copy regions far away from duplicons.
