More frequent dosing does not increase activity.
Patients without heart risks may be safe even with more frequent dosing, these data suggest.
Reduced doses and more frequent dosing could dilute out the adverse effects and still produce some beneficial effects.
They could sleep through the night — a crucial improvement over conventional painkillers, such as morphine, which require more frequent dosing.
The impact of missed doses is decreased by more frequent dosing despite the fact that compliance decreases with increased dosing frequency.
In treating patients with IBS, it may be possible to harness the placebo response and maximize therapeutic response rates by more frequent dosing.
More research is needed to understand the kinetics of BCG's effects, including whether more frequent dosing of BCG can shorten the lag time and if the systemic delay but durability of the clinical response is related to co-infection of stem cells that then create an entire immune reservoir for blood sugar regulation.
But for chronic viral infection, the antibody infusion requires a high-level dose (20 30 mg/kg, > 1 g/dose) and more frequent dosing to effectively eradicate the circulating virus, which may induce severe adverse events in patients.
Increased time above MIC may be achieved by more frequent dosing or by changing the mode of administration from an intermittent bolus injection to either an extended or continuous infusion.
GLM avoids the more frequent dosing required of some TNF inhibitors such as adalimumab and eliminates the expense and time commitment of outpatient infusions required for other TNF inhibitors such as infliximab.
Compared to MDMA and methamphetamine, bath salts require more frequent dosing to maintain the high.
