Sentence examples for more frequent development from inspiring English sources

Nevertheless, microvasculopathy which is due to medial rather than endothelial disease or a combination of both [4] is most probably responsible for the more frequent development of cardiac allograft systolic dysfunction in HTx patients presenting with inhomogeneous perfusion in SPECT imaging.

Just like in the whole group, males dominated in the group of patients who underwent CVVH; they were admitted to the hospital significantly later in the course of the disease and had significantly higher IAP measurements on admission, with more frequent development of necrotizing forms compared to patients who did not undergo CVVH.

This situation predisposes domesticated hedgehogs to more frequent development of tumors, including oral cavity.

The poor clinical prognosis of these patients has been linked primarily to the more frequent development of heart failure (HF) [ 2, 3].

Although the MT KRAS tumors showed a trend for more frequent development of peritoneum-only metastasis (13.5% vs. 27.9%; P = 0.062), it was not statistically significant (Table 6).

They were also more likely to be "sicker" as evidenced by a higher Charlson index, more visits to the PCP, more hospitalizations, and more frequent development of complications between baseline and follow-up (Table 1).

Thus, the cells containing these aberrations will become more frequent during tumor development than cells with other aberrations at the same locus not promoting proliferation or doing so to a lower extent.

Natural polymorphisms in HIV-1 subtypes have been postulated to play an important role in drug resistance pathways [66], including the propensity of HIV-1 subtype C virus that is predominant in Sub-Saharan Africa [67], for more frequent and rapid development of the K65R tenofovir-resistance mutation, noted by some investigators [68], [69] though not by others [70].

Natural polymorphisms in HIV subtypes may play an important role in drug resistance, including the propensity of HIV subtype C virus that is predominant in Sub-Saharan Africa for more frequent and rapid development of the K65R tenofovir-resistance mutation noted by some investigators [44], though not by others [45].

More frequent cell division during development can result in enhanced fixation of mutations because of the reduced time available for repair of DNA lesions, and clonal expansion of mutant cells gives a larger population of mutants (Slikker et al. 2004).

Using the available information instead of a randomised, controlled trial to identify a clinical effect or to solve a clinical problem has been described in the literature and may be a more frequent occurrence with the development of the automatic collection of a vast quantity of data at the bedside [ 28].