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In critically ill patients, the optimal effective circulatory volume may be difficult to determine, and as a consequence pulmonary oedema may be a much more frequent complication of RBC transfusion than in other patient populations.
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The understanding of vascular supply to the spinal cord is important given that the evolution of surgical approaches to the spine may bring along the potential for more frequent complications, especially a rare but devastating complication: that of spinal cord ischemia or infarction.
Those who died received greater inotropic and ventilatory support and developed more frequent complications (table 5).
More frequent complications of LABG include gastric erosion or perforation, band slippage or migration, esophageal dilation, port problems, incisional hernias, and acute respiratory distress and pulmonary embolism (44).
Suboptimal self-management (10), out-of-range glycemic control (11– 13), and more frequent complications and hospitalizations (14, 15) are of substantial concern during the transition years.
Higher case fatality and more frequent complications warrant more intense monitoring and a low threshold for additional investigations to diagnose concomitant invasive bacterial infections, including chest X-ray, blood culture, and lumbar puncture with CSF examination.
Compared with noncarriers of this mutant form, carriers exhibited significantly more frequent familial incidence (55% vs 15%, P = 0.035), younger age of presentation (40 years vs 51 years, P = 0.048) and more frequent complications (55% vs 10%, P = 0.049).
The survey data and expert interviews indicated a slightly higher prevalence of diabetes and hypertension among higher socioeconomic groups, but a higher incidence and more frequent complications and comorbidities in lower socioeconomic groups.
It is recognized that the hard brittle bone, often without a normal medullary canal, makes arthroplasty implantation difficult, may compromise the outcome and lead to more frequent complications [ 26].
Unless early and sustained blood glucose control can be achieved, higher rates of diabetes with earlier age of onset will result in more frequent complications from diabetes with resultant higher costs to quality of life and the health care system.
Yet a large interventional trial testing the survival impact of therapy escalation in sepsis patients in whom PCT did not decrease appropriately could not show a benefit for PCT-guided escalation [ 12]; in fact, due to prolonged antibiotic therapy, patients in the intervention arm suffered more frequent complications including renal impairment and more ventilation days [ 25].
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