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The NCCN guidelines recommend that 800 cGy in one fraction be utilized over a more fractionated regimen, such as 3,000 cGy in ten fractions, for nonvertebral metastases.
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Two or three injections of ME2303 starting from day 7 conferred a greater antitumour effect than did more fractionated or single-dose regimens.
In this study, total doses of 63-84 Gy E proton radiotherapy were applied in a fractionated regimen using 13 to 27 fractions.
A rat model for Pseudomonas sepsis demonstrated that peak concentration/MIC ratios >20 1 once per day produced significantly (p<0.5) better survival which may result in the selection of a mutant with altered topoisomerase than did regimens using the same dosage on a more fractionated schedule (52 ).
Radiation therapy consisted of a conventionally fractionated regimen to a total dose of 60 Gy, administered in 30 daily fractions of 2 Gy, with or without volumetric modulated arc therapy.
"This is much more fractionated than most people could imagine, with multiple, independent moving parts, and when you have that universe of networks, you can't have a one-size-fits-all approach".
This trend is almost parallel to the mixing trend between DMM and fluid and shows that Cl is more fractionated than F during amphibole-bearing wehrlite melting.
Moreover, no significant repopulation occurred during the longer overall treatment time of the fractionated regimen.
The dose is delivered in a fractionated regimen, usually twice daily, over 5 7 days.
Repopulation occurring during a protracted, fractionated regimen helps to spare normal tissues but is a potential danger for the control of tumor.
Owing to a conventionally fractionated regimen acute and early late toxicity was moderate as indicated by late effects not exceeding grade 3.
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