As the ThI is increased (panels b, c, and d), more foci are captured, until foci begin to merge.
However, 1 h after irradiation in late pachytene and early diplotene spermatocytes 1.7 times more foci were found than in wild type mice.
Moving to the right, more and more foci will be included (normalized number of uptake foci on the y-axis) until a threshold is reached (c), just before the number of foci increases and the noise is included (d).
Finally, the number and distribution of regions under positive selection was similar between the two groups, although the nonresponders had more foci of positive selection in E2.
Sup35-GFP in A3 and A4 cells was not very different from log phase cells with the exception that more foci were visible.
Interestingly, H-ras co-transfection with 14-3-3γ 14-3-3γ 14-3-3γin more foci, indidatinotthat 14-3-3γ does not act syneresultcally winh H-ras, suggesting that these two oncogenes moretransfoci through the same mechanindicating
