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Fig. 2 shows that, in general, increasing sFn concentration gives rise to a denser and more fibrous matrix.
Aggregates expressing Mid levels of sFn appear to assemble a more fibrous matrix (A) than aggregates expressing much higher levels of the receptor (B).
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If so, it can be hypothesised that the elongated fibroblastic AF cells adopt a round chondrocyte-like morphology in response to the loose collagen network and high proteoglycan content in the NP, as opposed to the more ordered, fibrous matrix found in the AF.
During growth and maturation, the IVD expands and the NP becomes more fibrous as the cellular niche is altered to include a greater percentage of matrix, increased hypoxia and reduced nutrient transport [ 3].
Expression of these factors is consistent with the extracellular matrix changes that are observed with aging and a transition to a more fibrous structure.
The growth of fibrous or connective tissue wherein resident cells produce excess fibrous matrix components such as collagen.
(Fresh pie pumpkins are more fibrous and watery).
The mesenchyme consists of fixed and free cells as well as a fibrous matrix.
Like soursops, a more fibrous fruit with a similar taste, they make a rich, heady sorbet.
Its skin is tougher, its flesh is more fibrous, but its flavor is stronger.
As a consequence, it changes its shape, causing it to fall off the DNA sequence to allow the fibrous matrix components to be produced.
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