Sentence examples for more favourable safety from inspiring English sources

Importantly, CEN1 HC had a more favourable safety profile compared to the original peptide, with no lytic activity observed against mammalian cells at the concentrations tested, thus showing a clear dissociation of antibacterial and anti-eukaryotic cell activities.

In combination, lower dosages could be used resulting in greater efficacy than single medication with a more favourable safety profile than higher dosages of individual drugs.

It will be of significant interest in the future to determine whether the tumour-specific homing identified in this study translates into a more favourable safety profile for the drug.

Adenoviral vectors are associated with several safety issues likely to prevent their clinical application for non-malignant diseases, given the availability of naturally occurring or engineered AAVs with significantly more favourable safety profiles.

This results in a more favourable safety profile, and facilitates maintenance of the correct dosing schedule and completion of the administration cycles (Norton, 1988, 2005; Burstein et al, 2000; Stammler et al, 2001; Wenzel et al, 2002).

Anastrozole was also associated with a more favourable safety profile vs tamoxifen, including a significantly lower incidence of endometrial cancer, thromboembolic events and vaginal bleeding/discharge albeit with increased risk of arthralgia and bone fracture (ATAC Trialists Groupp, 2005).

7 The later introduced cyclooxygenase-2 selective inhibitors (C2SI) exhibit a more favourable gastrointestinal safety profile, 8 albeit with individual differences.

Hence, selective COX-2 inhibitors like celecoxib and rofecoxib provide a more favourable GI safety profile with similar efficacy as compared to non-selective NSAIDs in patients with OA [ 9, 10].

Both gemcitabine/docetaxel and gemcitabine/paclitaxel are active regimens for metastatic breast cancer but it was unclear which of the two combinations has the more favourable efficacy and safety profile.

18 Following the rationale that arguments for the polypill are based on the expectancy of a more favourable benefit versus safety profile, we assumed that, in a situation where a polypill would be available, it would be considered to lower the threshold for prescribing preventive medication.

A mean score was computed for each subscale; higher scores indicate a more favourable culture in patient safety.