Sentence examples for more extreme codon from inspiring English sources
As a result, the PparoA1optimized has got a more extreme codon bias, with a CAI value higher than the PparoA1 in tobacco (>0.9, Fig. S1).
In these small organisms, highly expressed genes are found to have more extreme codon bias, where codon bias denotes non-equilibrium usage of up to six synonymous codons encoding for the same amino acids, with 'preferred codons' in highly expressed genes corresponding to the most abundant isoaccepting tRNAs.
Further, codon bias in many organisms is more extreme within four fold redundant codon systems, and this codon bias appears to be more likely to change over geological time.
This artifact results from the maximum possible value being assigned to genes with codon composition identical to pre-selected set of "optimized" genes, even though other genes may show more extreme enrichment of the optimal codons.
May this trend simply be a consequence of codon choice becoming less flexible at more extreme GC content?
In contrast to the first two codon positions, where A/T nucleotides may be required to specify amino acid identity, GC variability is much more extreme at 3rd sites (Muto and Osawa 1987) so that encountering a 3rd site T in a high-GC genome is comparatively rare.
"Contortion is more extreme".
Everything is more extreme.
It's getting more extreme.
Everything is far more extreme".
