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More extracellular matrix and a higher level of alkaline phosphatase expression were found on the porous samples than on the Ti sheet.
Furthermore, CMS samples demonstrated improved tensile mechanical properties following four weeks of culture, suggesting the generation of more extracellular matrix within the polyurethane constructs.
This method could regulate gene expression to synthesize more extracellular matrix type IV collagen, paving an important way to provide a favorable environment for BCEC cultures.
Consistent with the in vitro studies, the "BMP-7 + DXM" group presented more extracellular matrix and hard tissue formation than the "DXM" group after 8 weeks of ectopic implantation in nude mice.
One possible explanation for the additional delay in wound healing observed in Mmp13 Plau double-deficient mice is that the cleavage of one or more extracellular matrix components, which is critical for keratinocyte migration, can be achieved by either MMP-13 or uPA.
They produce more extracellular matrix (ECM) components and more regulators of the ECM turnover.
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In addition, more extracellular matrices were produced by the differentiated cells over a period of 14 days on/in the PhaP-RGD coated scaffolds evidenced by scanning electron microscopy imaging, enhanced expression of chondrocyte specific genes including SOX-9, aggrecan and type II collagen, suggesting the positive effect of RGD on extracellular matrix production.
Under stimulation by transforming growth factor-beta, bone marrow-derived MSCs expressed more cartilage extracellular matrix proteins and exhibited a more mature chondrogenic phenotype than adipose-derived MSCs.
Interestingly, electron microscopy showed larger chondrocytes and a more abundant extracellular matrix.
Seeding with fibrin resulted in less loss of soluble collagen into the medium and a more mature extracellular matrix in a shorter period of time.
The MLCs exhibited a much more extensive extracellular matrix than monolayer cell cultures.
More suggestions(15)
more flexible matrix
more homogeneous matrix
more extracellular current
more mineralized matrix
more sophisticated matrix
more extracellular polymeric
more extracellular region
more layered matrix
more extracellular PknB
more calcified matrix
more difficult matrix
more slack matrix
more structured matrix
more extracellular mass
more severe matrix
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