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Here we performed western blotting on a more extensive panel.
However, such an investigation would likely require analysis of Arp2/3 complex mutations and of a more extensive panel of VCA mutations.
A detailed analysis of these tumours, using a more extensive panel of IHC markers to delineate the basal phenotype, is warranted.
Perhaps by using a more extensive panel of modifications or a genome-wide screen, other candidate molecular markers for the ALT phenotype could be uncovered in future experiments.
The questionnaire was part of a more extensive panel survey administered by The Research Institute of the Norwegian Medical Association every other year.
With less constrained resources, in particular original sample DNA, innovative techniques such as methylation microarray technology could be used to highlight further targets worthy of investigation and validation as part of a more extensive panel of TSGs.
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PGx testing for these drugs is typically included in a more extensive screening panel, as the cost of including these variants in a genetic test is negligible.
It should be noted that genotyping outbred mice or mice of mixed backgrounds is possible, but may require the use of a more extensive marker panel.
If no pathogenic mutations are identified, a more extensive glomerular gene panel or exome sequencing could be performed; and (2) to restrict the targeted sequence to exons and intron boundaries as the assessment of the pathogenicity of deep intronic variants is challenging and their involvement in the disease speculative.
The data from this analysis on a limited number of primary tumor samples of the three major breast cancer subtypes essentially mirrors the quantitative RT-PCR results performed on a more extensive and well annotated panel of breast cancer cell lines.
29 35 In this study, CDX2 was shown to transactivate a 9.3 kb Cdx2 promoter which better mimics the endogenous promoter by covering a much more extensive regulatory region in a panel of gastrointestinal cell lines.
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