These more extensive multivariate cost and illness analyses are the subject of a conference presentation [ 33] and a manuscript in preparation.
Therefore, we postulate that during EAEC and rotavirus co-infection, both pathogens act simultaneously on the human gut, possibly at different sites, thus resulting in more extensive enteritis, and severe illness.
Brain imaging studies have identified structural changes both early in the presentation of the illness and more extensive changes later in the course of the illness [ 1].
The cost of illness is possibly more extensive than has previously been recognised [ 5, 12].
The sample of patients participating in the initial survey included 1144 adults; however, analyses presented here were limited to the subset of 620 who completed a more extensive survey module including questions about chronic illness management and cell phone use.
And for parents with children on machines, these mothers need more training; and when the children have a potentially fatal illness, such as diabetes, the training is more extensive.
The emerging field of narrative medicine proposes that patients can be treated correctly only when they can tell the story of their illness, often in the context of a more extensive autobiography.
Research suggests the higher the allostatic load, the more extensive the physiologic dysregulation, and a higher the risk of illness and premature death [ 21, 27, 29- 32].
More extensive cognitive impairment may be associated with a more severe course of illness, including a greater number of episodes, history of psychotic symptoms, and longer duration of illness [ 22- 24].
Specifically, we hypothesised that grey matter changes would be more extensive in those with discrete disorders (and as such at later stages of illness), as compared to those with earlier sub-syndromal or attenuated syndromes.
