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Although Pten heterozygosity per se results in low-grade PIN in mice [ 151], Schutzman et al. [ 140] showed that concomitant inactivation of the Sprouty genes (Spry1 and Spry2) accelerated emergence of PIN and promoted development of more extensive, high-grade phenotype along with the transition to invasive cancer.
On the contrary, the fatigue behavior of Epoxy-based laminates at Tmore extensive at high frequency.
Tip-induced wear was more extensive at higher applied load, lower scan rate and at higher scan line densities.
The eastern region is more extensive and higher, with several peaks over 5,000 feet (1,500 metres), culminating in Mount Bogong (6,516 feet [1,986 metres]).
Thus, as individuals develop more extensive and high-quality relationships in the workplace, the increased affective attachment will lead to more embeddedness in the organization and less intention to leave (Mossholder et al., 2005).
Design of surveillance approaches requires a balance between demands for more extensive and higher quality data and the feasibility of collecting such data.
While B cells appear to represent the predominant lymphocyte during early breast cancer progression [ 34], infiltrating T lymphocytes (both CD4+ and CD8+) are more extensive in higher grade DCIS and invasive carcinomas [ 46].
We demonstrated that hypermethylation occurs in the majority of PCa samples, is more extensive in high-grade samples, and correlates with the risk of PSA failure in a validation cohort.
Editors of children's programmes from the Radio Television of Serbia (RTS) and Radio Television of Croatia (HRT) pointed out that their small teams (RTS - 6, HRT - 4 persons) represent one of the barriers for taking steps towards change, while representatives from the FYR Macedonia, Bosnia and Herzegovina and Serbia singled out the lack of funding for more extensive and higher quality programmes.
"I disagree with it, because I think Al Jazeera has obviously long since established itself as a really distinguished and effective newsgathering organization -- and by the way, its climate coverage has been far more extensive and of high quality than any of the networks here".
However, recent data suggest that more extensive lymphadenectomy with high grade tumours may actually confer a survival advantage[ 10 ].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com