This mechanism alone offers an explanation for how PO inhibition could confer Li+ resistance, however our observations on gene expression suggest a more extensive effect of PO on expression of multiple inositol synthetic genes.
However, we found that it was the surgeons' perceptions of their own role in the health care system that seemed to have a more extensive effect on certifying sickness absence, and, therefore we chose to analyse this emergent domain.
These results could be explained by the fact that different experimental treatments were used on the cells for each experiment; cells transfected with shRNA Kaiso plasmids suffered from the effectiveness of transfection, while treating with a Kaiso antibody could exert more extensive effects throughout the culture.
Jitter had more extensive effects on the trajectory classifiers, especially at small timescales.
Certainly, targeting an EWS/FLI1 mediator which is more upstream, such as GLI1, could be expected to have more extensive effects than targeting a gene further downstream in the process.
One can postulate that either reactive 'passenger' inflammatory leukocytes are implanted at the time of surgery, that other cells in the donor allograft are responding, or that the activation of cells in response to CCR2 activation in the donor allograft has more extensive effects than are generally understood.
In the two reconstructed studies where cases and controls were collected independently using different designs, we observed more extensive confounding effect by PS with over-dispersion factors of 1.090 and 1.062.
The more extensive regenerating effect of PTH on bone is therefore restricted to the implant interface alone, with a quiescent response in the surrounding remodeling bone (Skripitz et al. 2000a, b).
Elafin was safe and well tolerated in this high-risk clinical setting and post hoc analysis indicated reduced myocardial injury at 6 h, raising the possibility that more extensive treatment effect could have been seen with multiple doses or bolus and sustained infusions.
We hypothesize that in heavily human-modified landscapes, more extensive edge effects combined with other human disturbances on tree mortality and carbon stock may contribute to overall high levels of degradation, reducing differences between edge and interior habitats.
The obtained in-service parametric model coupled all of the main factors that had significant impacts on the damping characteristics, so that the model could be useful in more extensive parameter effects analysis, optimal specification and product design optimisation of hydraulic dampers for track-friendliness, ride comfort and other high-speed transit problems.
