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Compared with the serum effect, medium B also permitted neurosphere attachment onto the substrate surface and cell migration out of neurospheres extensively, but enhanced more extensive cell division and slowed down NSPC differentiation to generate a confluent NSPC monolayer.
Our analysis revealed that, at 25 dae, Aβ42Arc fly brains showed more extensive cell loss than that in Aβ42 or Aβ42art brains (Figures 3A F).
We chose icv delivery of cells since it is less invasive, allows to deliver more cells and produces more extensive cell seeding than the local intraparenchymal injection.
The fact that Wnt8 knockdown doesn't recapitulate the more extensive cell proliferation deficit displayed by SpRunt-1 morphants is probably attributable to the fact that wnt8 is expressed in a more limited domain that contains only a subset of proliferating cells.
A more extensive cell death response could cause opposite effects on the outcome of biotrophic versus necrotrophic plant-pathogen interactions.
The lower levels of viremia generated by strain FE3-7c may reflect the more extensive cell culture passage history of this isolate.
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The higher number of B cells in TCR-TgA mice could present antigen to T cells more effectively and led to a more extensive T cell activation).
Joint grading was as follows [ 19]: normal, mild (minimum inflammatory cell infiltration and synovial hyperplasia with some cartilage loss), moderate (more extensive inflammatory cell infiltration and synovial hyperplasia with considerable bone erosion) and severe (complete destruction of joint architecture).
In preliminary experiments in which we extracted total lipids from V1 V5 by the Bligh-Dyer method (23), we found that V5 lipids induced more extensive endothelial cell apoptosis than did V1 V4 lipids (data not shown).
Compared to these models, PyMT induces more extensive β-cell hyperplasia with a ��30-fold increase in islet area without significant change in cell size and blood glucose level, and mice do not develop malignant β-cell tumors.
An explanation similar to that reported by Willoughby et al. [ 18] who concluded that mild inflammatory injury stimulates epithelial proliferation, whereas more severe inflammation depresses it, perhaps due to more extensive progenitor-cell damage.
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