The range of validity of the overall model will be limited to the smallest range of validity of any of its sub-models, so the more sub-models, the more extensive the amount of validation required.
Thus, the extent of terminal loss in the striatum seems to be much more extensive than the amount of loss of substantia nigra pars compacta dopaminergic neurons, suggesting that the striatal dopaminergic nerve terminals are the primary target of the degenerative process and that neuronal death in Parkinson's disease represents a 'dying back' pathology (Dauer and Przedborski, 2003).
Unfortunately, for large-scale HPC applications, the burst buffer SSDs can be worn out much more quickly given the extensive amount of data written at every checkpoint step.
The number of cancer genes identified does not reach its maximum until all the tumors are included, indicating that significant numbers of known (and by extension unknown) cancer genes might still be found by performing more extensive studies with larger amounts of tumors.
Clearly, a more comprehensive decomposition of the modularity and community structures within a protein interaction network will provide a more extensive result set, given the large amounts of methodology and data from related systems biology studies [27].
Of these, stem cell-mediated tissue repair is one of the most promising areas, and has received an extensive amount of attention for more than a decade [5].
However, more extensive evaluations are required to determine the amount of hand-labeled tweets needed to approach the "maximum" performance, e.g., the inter-annotator agreement.
Consequently, parents whose baby required more extensive resuscitation were often given the least amount of information.
This can be explained by a larger amount of foreign material and more extensive exposure of soft tissues.
Their model also suggests Titan's shell has seen an extensive amount of erosion, with features carved more than 650 feet (200 meters) deep on it surface.
