Sentence examples for more extensive alterations from inspiring English sources

Even more extensive alterations were made between 1884 and 1885.

Patients with AD exhibited similar but more extensive alterations, while no significant changes were observed in dysexecutive MCI patients.

In the cases of infection of susceptible ("Piel de sapo") and resistant (pat81) melons by M. cannonballus, more extensive alterations in gene expression seemed to occur in the susceptible than in the resistant accession.

These findings all point to more extensive alterations in lipid metabolism caused by neonatal parathion exposure in females, associated with increased susceptibility to metabolic reprogramming that resulted in a net catabolic response, as opposed to the biphasic response seen in males.

It is conceivable that the more extensive alteration of gene expression in the colon (GSDMA, GSDMB, and LRRC3C) compared with that in the CD ileum (ZPBP2) reflects the fact that colonic inflammation may occur in both CD and UC, whereas ileal engagement is restricted to CD.

Alt-EJ operates with speed and fidelity markedly lower than c-NHEJ, causing thus with higher probability chromosome translocations, and generating more extensive sequence alterations at the junction.

In addition, lungs ventilated with high peak pulmonary artery pressures and flows exhibited more extensive histologic alterations and edema formation than did those subjected to the same ventilatory pattern but at lower peak vascular pressures and flows [ 25] (Fig. 4).

Thus, biomarker discovery has to shift toward an integrative network-based approach that accounts more extensive genomic alteration.

Among AD animal models, TgCRND8 mice showed a more extensive spectrum of synaptic alterations compared to other AD mouse models, characterized by mutations only in the APP gene (APP23 and Tg2576 mice).

MD was found increased (p < 0.01, corrected for multiple correlations) in regions where FA alterations were found, but the alterations were more extensive involving more frontal, parietal and temporal juxtacortical white matter (Figure 1, second row).

Some areas of cortical thickness alterations were more extensive in patients with left mTLE, including ipsilateral mesial temporal and temporo-occipital cortices.