Sentence examples for more essential proteins from inspiring English sources

A plausible explanation for this parallelism between non-support of propagation and inhibitory action by the same Trp-analogue is that its failure to support cell propagation might be the consequence of its proteome-wide incorporation into cellular proteins leading to malfunction in one or more essential proteins.

MCC captures more essential proteins in the top ranked list in both high-degree and low-degree proteins.

Up to top 10% of proteins, ION detects more essential proteins with high-connectivity than the six centrality methods (DC, IC, EC, SC, BC and CC).

As indicated in the top part of Table 2, for each top percentage of proteins, ION finds more essential proteins with low-connectivity than eight other existing centrality methods.

In fact, the very importance of a protein is sometimes quantified by its average rate of evolution as more essential proteins involved in core cellular processes tend to evolve at slower than average rates.

(3) In top 100 of ranked proteins, ION can not only detect more essential proteins ignored by the eight other existing centrality methods but also exclude a large number of nonessential proteins which can't be ignored by these methods.

Knockdown of one more essential protein in autophagy pathway may possibly improve accuracy in technical way.

Additionally, it has been found that the multiprotein complexes are enriched for essential genes (Semple et al. 2008), and proteins those are present in several protein complex assemblies have a tendency to be more essential than proteins that are present in fewer protein complex assemblies (Pereira-Leal et al. 2006).

More detailed information about these proteins and the corresponding complexes is listed in the Additional file 3. From Figure 7 and Table 4, compared with PeC, NC and DC,we can clearly see that more true essential proteins are detected by ION, but also more of these proteins ranked in top 100 by ION belong to the complexes with certain biological functions.

As shown in Figure 6, ION can detect more different essential proteins than these methods.

Therefore, the regulators which participate in crosstalk motifs tend to regulate hub proteins, which are usually more essential than non-hub proteins [ 39- 41], and modular proteins, which usually form important protein complexes or modules in human PINs [ 42- 44].