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Use of the DAVID Bioinformatics Resource showed that the overlapping genes are even more enriched for voltage-gated channels (7.3-fold enrichment, P<10−11) and for genes expressed during development (2.4-fold enrichment, P<10−18).
The implicated list was more enriched for actin SDIs than the entire nonessential gene deletion set, suggesting functional enrichment in genes that show SDI with actin.
These results demonstrate that the compounds from VS of the focused set are not only more enriched for kinase-like compounds than the random screen, but also interact better with the kinase binding pockets.
No single species is more enriched for "interesting" genes than any other species, but the traditional tractability of studying these interesting genes was centered on the model species with excellent molecular, physiological, biochemical, cell biological and genetic toolkits.
Cells expressing both PDGFRα and Sca-1 (PαS) are MSCs that are 120,000-fold more enriched for clonogenic cells (CFU-Fs [10], [11], [12]) than unfractionated bone marrow [13], [14].
In human breast cancer cell lines, it has been found that an ALDEFLUOR-positive CD44+ subpopulation of CD133+ cells was more enriched for tumor-initiating cells than ALDEFLUOR-negative CD44−/CD133+ cells [42].
Similar(14)
He postulated that individuals who begin life with the advantage of genes which increase their ability relative to the average may also be born into homes that provide them with more enriched environments, for instance being more committed to learning and teaching.
Hence, oral and written data were collected to capture a more enriched data pool for analysis.
We used the same threshold of evidence against the null hypothesis (p-value< = 0.01) and identified more enriched KEGG pathways for switch-like genes as seen in Table 5 than that study [77].
On Monday, Iran said it was prepared to return to negotiations on an international deal to swap some of its lower-enriched uranium for more enriched uranium "without conditions," according to the official IRNA news agency.
These results present for the first time evidence that TEs are more enriched in P450 genes responsible for xenobiotic metabolism as opposed to P450 genes involved in ecdysone biosynthesis and developmental regulation.
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