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For example, more elucidation is required on the exact stoichiometry of TatA proteins per substrate and complex before such information can be incorporated into iJL1678-ME.
It is likely that such genetic characterization of EIEE cases will lead to a better understanding of genotypes and phenotypes, as well as more elucidation of disease mechanisms and therapeutic strategies.
In addition, our previous data suggested that early conversion from CsA to SRL promotes a better cardiorenal profile than late conversion [ 27], whose mechanisms and biomarkers deserve now more elucidation.
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More complete elucidation of these processes is indispensable for the understanding of β-cell function and abnormalities in pathologies, such as type 2 diabetes.
The resulting more definitive elucidation of neuronal pathways and processes is facilitating the development of drugs that are better targeted to systems or receptors implicated in neurological disorders.
The more recent elucidation of the genetic basis of toxin and bioactive peptide synthesis paved the way for investigating its regulation both in the laboratory using cell cultures as well as under field conditions.
It was beyond the scope of this analysis to detail or quantify the risk of other cancers in surgery for presumed fibroids, but investigation should continue for a more thorough elucidation of the risks of all such tumors as well as the relative benefits of different surgical approaches.
Advances will require integration of different biomarkers such as genomics and imaging to provide for more adequate elucidation of the spatially varying location, type, and extent of diverse intratumor signaling molecules to provide for a rationale-based personalized cancer medicine strategy.
Potential societal benefits would include reduction in the cost of drug development, a reduction in the incidence of unexpected severe drug and environmental toxicity, and more rapid elucidation of the contributions of genes and the environment to phenotypes, including the validation of candidate disease alleles identified in population and personal genetics.
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In conclusion, a more definitive elucidation of the ascovirus and ascovirus-like origins will require further efforts in phylogenetics.
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