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Indeed, mTORC2 was more efficiently inhibited by GDC-0980 compared with NVP-BEZ235, resulting in inhibition of AKT activation.
Subtumoural insertion of the GEM-PU-PL12% membrane more efficiently inhibited the growth of CT-26 colon cancer than other membranes.
Physiological myocardial uptake was more efficiently inhibited in patients in the LF group compared with in the HEP group.
JFH1 core slightly more efficiently inhibited IPS-1/DDX3-augmented IFN-beta-induction than HCVO core (Fig. 4B).
Cell lines with high TfR expression significantly correlated with high degrees of modulation indicating that high TfR expressing tumor cells would be more efficiently inhibited by this combination treatment than low TfR expressing ones.
The ST activity is more efficiently inhibited when the reaction is performed with the full length substrate (strand transfer observed in 3'end processing assay Figure 4B) versus precleaved substrate (strand transfer assay, Figure 5), as previously observed by Marinello et al [12], suggesting again that it binds to a preformed complex IN-DNA rather than to the enzyme alone.
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Overall, our data indicate that hollow nanoparticles containing photosensitizers more efficiently inhibit hepatoma cells than free photosensitizers, through induction of apoptosis, both in vivo and in vitro.
Compared with CR, rapamycin more efficiently inhibits mTOR.
These results demonstrated that DHA can more efficiently inhibit NF κB activity than EPA.
We speculate that for this reason the targeted mutants more efficiently inhibit one essential pathway whereas the wild-type proteins partially inhibit two pathways.
Therefore, we hypothesized that longer chain docosahexaenoic acid (C22 6n-3 C22 6n-3e efficanntly inhibit the protein degradation by regulating PPAR γ/NF κB pathway in C2C12 moreubefficiently.
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