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Dietary EPA and DHA when esterified to phospholipids (PLs) are more efficiently incorporated into tissue PLs and seem to possess peculiar properties through specific mechanism(s) of action, such as the capacity to affect endocannabinoid biosynthesis at much lower doses than EPA and DHA in triglyceride form, probably because of the above mentioned higher incorporation into tissue PLs.
Although β-carotene and α-carotene were affected in a similar way by the cooking process, α-carotene appeared to be more efficiently incorporated into the micelles when olive oil was added to the samples.
Indeed, in Zucker rats, EPA and DHA from krill oil were more efficiently incorporated into heart phospholipids, compared to EPA and DHA from fish oil [ 31].
It is possible that some of the siRNAs employed in the present study were more efficiently incorporated into the RISC, and were therefore able to outcompete the others.
Therefore, siRNAs with unstable 5′ ends in the guide strands will likely have a high K2, which indicates that it will be more efficiently incorporated into the functional RISCs.
However, an increased bone uptake of Zr-cetuximab, compared with Y- and Lu labeled cetuximab, was observed indicating that Zr is more efficiently incorporated in the bone compared to the other radiometals (Y- and Lu).
Similar(51)
This finding indicates that n-3 PUFAs incorporated in phosphatidylcholine act on brain function more efficiently than those incorporated in triglycerides.
These results were also strengthened by measuring the stoichiometry of phosphorylation for LRRK2 and 4E-BP in the same reaction, where we found that LRRK2 incorporated phosphate more efficiently than 4E-BP again despite the latter being present at molar excess.
The nonnucleoside RT inhibitor -FTC has greater potency than 3TC because the -FTC-triphosphate is incorporated 10 times more efficiently than 3TC-triphosphate during HIV-1 RT-catalyzed RNA-dependent DNA synthesis [53].
Similarly, for Dpo4, the efficiency of dCMP incorporation, as determined by the kcat/ Km values, opposite S-cdG was only 0.06% relative to G (Table 6), but the nucleotide preferentially incorporated opposite S-cdG by Dpo4 was the wrong nucleotide dTMP, which was incorporated nearly 10-fold more efficiently than dCMP.
While other social networking services have long incorporated ways for group administrators to communicate more efficiently with their members, LinkedIn for whatever obscure reason never even bothered to create a feature that allowed admins to e-mail group members directly for the sake of sharing announcements.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com