Sentence examples for more efficient splicing from inspiring English sources
More efficient splicing of IgMPTB was observed with ΔNΔRS than with SF2/ASF (Figure 4, lanes 14 and 15), suggesting that the RS domain of SF2/ASF is not required for counteracting the function of the PTB site I silencing element.
Indeed, lower temperatures directly induce more efficient splicing and, as a result, an advanced molecular and behavioral phase [ 17, 24].
Whether the stimulation of expression occurs through the promotion of transcription, more efficient splicing, or enhanced export, remains to be determined.
It is hypothesised that nucleosomes positioned within exons, especially those with weak splice sites, cause RNA Polymerase II (RNAPII) to pause, enabling an interaction with the spliceosome and more efficient splicing [ 3].
Therefore, one could speculate that a more efficient splicing of the mutated as compared to the wild-type pre-mRNA may lead to the different mRNA and protein levels.
The disrupted splice site is now more efficient at splicing out the shorter intron, leading to the longer product.
The ratio of total transcripts to spliced RNA (a/c) and pre-mRNA to spliced RNA (b/c) was lower in Lsh−/− samples compared to WT samples suggesting that Lsh−/− cells were relatively more efficient in splicing than WT cells (Fig. 5B).
3) The statements that post-transcriptional splicing is more efficient or faster than cotranscriptional splicing (or splicing pre and post release) are also not supported.
Furthermore, our time-resolved results indicate that post-release splicing is more efficient than pre-release splicing, which may explain how the timing of intron removal might lead to different outcomes for the message.
This correlation is not particularly strong and have various explanations, for example, longer introns may be more efficiently spliced out or may be splicing is important for an efficient transport of mRNA.
Although in vitro splicing can occur, splicing is more efficient when coupled with transcription [ 2], suggesting that factors additional to the nucleic acid sequence are important for splice site recognition.
