"I think the states are making major progress toward a more efficient and effective regulatory system," said Joel Ario, the insurance regulator in Oregon and the secretary-treasurer of the National Association of Insurance Commissioners.
You would have a much more efficient and effective regulatory system than I think you will have when you try to tell people the exact amount of leverage they can have and try to set in stone numbers for all times.
Thus, this may demand the evolution of higher affinity (and/or more concentrated) TFs and more efficient cis-regulatory elements.
The reasons behind the lower glycemic variability in WFS patients may be manifold from more conservative treatment regimens ordered by their doctors to more efficient counter-regulatory mechanisms.
Mr. Cuomo has argued that those changes are necessary to create a more efficient and modern regulatory framework for businesses and better protection for consumers.
Furthermore, increasing scrutiny and accelerated approval pathways provide a driving force to be even more efficient with limited regulatory resources.
This co-regulation is essential in regulating a complex cell signaling network, and is more efficient than the regulatory pattern mediated by discrete miRNAs [40], [41].
This difference may be due to the larger effective population size (Ne) of Drosophila than of mammals [ 28– 30], which contributes to more efficient adaptive protein and regulatory sequence evolution in Drosophila [ 31– 33], and could similarly result in more rapid acquisition of adaptive functions by Drosophila duplicate genes.
Successful implementation of the MDEP recommendations should result in tools that can be used to enhance the ability of regulatory bodies to cooperate on reactor design evaluations, vendor inspections, and construction oversight, leading to more efficient and more safety-focused regulatory decisions.
