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DNA transposition-based strategies offer substantially more efficient random strategies and provide means to generate single-copy insertions, thus potentiating the generation of genome-wide insertion libraries applicable in genetic screens.
Lastly, the proposal distribution, which proposes a candidate state given a current state, is also improved to enable a more efficient random walk over the states.
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The new Tn5-based random mutagenesis system developed in this study is more efficient and random than previously reported C. perfringens random mutagenesis approaches.
It is more efficient than random meetings in a bar, and no one is asking, "Come here often?" So it may seem strange that the leading online personals company, Match.com, has started a new $25-a-month 25-a-monthon service -- to meet random people in bars.
The piggyBac transposon (PB) has been demonstrated to be an efficient mutagenesis tool in mammalian cells and mice (Ding et al., 2005; Wu et al., 2007) Compared with the commonly used retroviral vectors, PB transpositions in mammalian cells are more efficient and random (Wang et al., 2008).
Dictyostelium cells are about half as efficient as a straight-line search, and 1.6 to 2.4 fold more efficient than random walk searching.
"Template-directed ligation" should be significantly more efficient than "random ligation", so P TL > > P RL.
Another conclusion of this research was that introducing patchy or modular connectivity, with occasional long-range connections that have many end-point connections to a patch or module, was much more efficient than random (but sparse) connectivity, especially for large brains.
The proposed SBN technique is more efficient than a random sampling approach, due to the use of non-Bernoulli sequences of random permutations of fixed numbers of 1's and 0's in the representation of initial probabilities [ 41].
The DRS algorithm is clearly more efficient than the random search (Cao 2010).
Bhat [37] also found that 100 Halton draws are more efficient than 1,000 random draws for simulating an model.
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