It is possible to filter out or discount the vast majority of variants for dominant diseases when they can be observed in healthy relatives, making the interpretation much more efficient and conclusive.
Daniel MacArthur (Massachusetts General Hospital, USA) suggested a brute force approach that includes sequencing a large number of individuals, postulating that 'in order to understand one genome, we need to sequence tens of thousands of genomes.' Other speakers suggested alternative, more efficient approaches to rare variant interpretation.
As such approaches are proven valid over time, they are expected to streamline the risk assessment process itself, allowing for more efficient assessments and read-across interpretations among chemical groups that share MOAs.
In addition, confirmatory tests might be rendered more efficient by combining isotope ratio mass spectrometry with refined interpretation criteria for positivity and subject-based profiling of steroids.
In this case, where precision in sample classification is favored to biological interpretation, higher values of α are generally more efficient.
Interpretation BCI-controlled DBS is tractable and can be more efficient and efficacious than conventional continuous neuromodulation for PD.
"My interpretation is that people who are more cognitively active have more efficient brains," Dr. Jagust said.
City officials disagree with that interpretation and say they are being pushed to improve recycling efforts and become more efficient in controlling what winds up in landfills.
