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This, in turn, results in increased stability of the misaligned substrate, allowing for more efficient extension by the polymerase.
Addition of various concentrations of PCNA (up to 6.6 nM), at sub-equimolar concentrations (compared to Pol δ), resulted in more efficient extension (Supplementary Fig. 1, lanes 5 8).
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However, kinetic analysis of the next-base insertion event showed that extension of the M1dG·dC pair, while inhibited ∼30-fold relative to that of unmodified substrates, is ∼8-fold more efficient than extension of the M1dG·dA pair when dC is 5′ to M1dG (Table 3).
Theoretically, viewing horizontally orientated presentations of BT image volumes makes reading more efficient because the extension of the visual field is better aligned with the viewing area of the monitor.
It is desirable to propose an extension method more efficient in preserving the properties of extended operator.
However, compared to the S-cdG T miS-cdG Tone-base extension was mispairficient for the S-cdG:C pair.
(B ) When telomerase is recruited to a telomere through the Ku-Sir4 pathway, subsequent Est1-Cdc13-mediated recruitment to the end of the telomere becomes more efficient, resulting in increased telomerase extension of telomeres.
Future evolutions of this extension may evaluate more efficient and semantically accurate encoding of notifications.
If you find that you are looking for data on a lot of sites as you surf the web, the extension will be far more efficient.
These findings extend the correlation between chronological lifespan extension, less frequent apoptosis and more efficient G1 arrest.
Offloading the elbows and loading the shoulders more may make for a more efficient transfer particularly for individuals who lack elbow extension function.
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CEO of Professional Science Editing for Scientists @ prosciediting.com