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Furthermore, the higher serum levels of IgG2a, which is regulated by Th1-associated cytokines[37], in sHA.GCN4pII vaccinated mice might suggest that the finding of more efficient clearance of virus could be related to the effector functions of IgG2a such as complement activation and Fc receptor binding[23], [38], [39].
The increased access to blood permits greater oxygenation of hepatocytes and more efficient clearance of drugs and other xenobiotics.
Collectively, these results suggest that the age-associated deposit promotes cytosolic quality control by enabling more efficient clearance of degradation substrates.
However, the rebound in TS activity in C26-B was larger and longer lasting, analogous to the more efficient clearance of 5-FU from RNA (see above).
We also show the effect of passaging the cells during Plasmocin treatment: cells that were passaged show significantly fewer punctate bodies, suggesting a more efficient clearance of contamination.
The advantage of utilizing OM for the preparation of UCNPs lies in its ability to produce ultrasmall UCNPs that are attractive for bioimaging due to their more efficient clearance from the body.
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Premenopausal levels of oestrogens in women may promote more efficient renal clearance of urate [ 15- 17].
If sex alleviates mutation pressure through more efficient mutation clearance, then the sexuals should be higher in fitness when compared to asexuals.
We show that in Stat1-S727A miceNK micellsK cells display higher cytotoxicity toward a broad panel of target cells, leading to more efficient tumor clearance.
We have reported these differences in Ca2+ dynamics previously in rat hippocampal neurons which we attributed to more efficient Ca2+ clearance from dendritic regions [48].
Notably, we found that IL-33-treated mice developed significantly increased neutrophil infiltration in the peritoneal cavity (fourfold) and more efficient bacterial clearance than untreated mice (n = 10) after CLP.
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